The SZ-100V2 nanopartica series instruments are flexible analytical tools for characterizing the physical properties of small particles. Depending on the configuration and application the system can be used as a particle size analyzer, or also used to measure zeta potential, molecular weight, (MW) and second virial coefficient (A2). Typical applications for the SZ-100V2 include nanoparticles, colloids, emulsions, and submicron suspensions.
Particle size analysis is performed by dynamic light scattering (DLS). Depending on the physical properties of the sample, the dynamic range is 0.3 nm – 8 µm. The lower limit is influenced by concentration, how strongly the sample scatters light, and the presence of large, unwanted particles. The upper limit is influenced by the density of the sample since DLS is modeled on all motion coming from Brownian motion, not gravitational settling.
SZ-100 Product Overview
The charge on the surface of particles is characterized by the SZ-100V2 by measuring the zeta potential of a suspension. The sample is injected into a disposable cell and a measurement of the particle electrophoretic mobility results in the calculated zeta potential. The zeta potential of the sample is most often used as an indicator of dispersion stability.
The same instrument can also be used to measure the molecular weight and second virial coefficient of proteins, polymers, and other molecules. The user prepares several solutions with known concentrations and then uses the system in a static light scattering mode to create a Debye plot, which results in a calculation of both MW and A2.
Particle size, zeta potential, molecular weight, and second virial coefficient all in one instrument
Wide range of particle sizes and concentrations
Particles size measurements at both 90° and 173°
Multiple particle size measurement modes for working with small particles and weak scatterers
Small volume cells for both particle size and zeta potential